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  2. Cortisol awakening response - Wikipedia

    en.wikipedia.org/wiki/Cortisol_awakening_response

    Waking up earlier in the morning increases the response. [11]Shift work: nurses working on morning shifts with very early awakening (between 4:00–5:30 a.m.) had a greater and prolonged cortisol awakening response than those on the late day shift (between 6:00–9:00 a.m.) or the night shift (between 11:00 a.m.–2:00 p.m.). [12]

  3. Prostaglandin antagonist - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_antagonist

    Studies on NSAIDS have shown that it can cause acute kidney injury by inhibiting prostaglandin production. The decreased levels of prostaglandins increases the risks of interstitial nephritis since there is lower blood flow to the kidneys. However, the risks of NSAIDs induced kidney failure is higher in people with diabetes or cardiovascular ...

  4. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    These NSAIDs, while reducing inflammation, also inhibit platelet aggregation and increase the risk of gastrointestinal ulcers and bleeds. [11] COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis , and some of these agents substantially increase the risk of heart attack .

  5. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    [86] [87] As with other NSAIDs, ibuprofen may be useful in the treatment of severe orthostatic hypotension (low blood pressure when standing up). [88] NSAIDs are of unclear utility in the prevention and treatment of Alzheimer's disease. [89] [90] Ibuprofen has been associated with a lower risk of Parkinson's disease and may delay or prevent it.

  6. How to Find the Best Treatment for Your Migraines - AOL

    www.aol.com/lifestyle/best-treatment-migraines...

    Triptans: After trying NSAIDs, triptans are the go-to drug for many people with migraines. “These are migraine-specific pain medications,” says VanderPluym. “These are migraine-specific pain ...

  7. Indometacin - Wikipedia

    en.wikipedia.org/wiki/Indometacin

    Indometacin's role in treating certain headaches is unique compared to other NSAIDs. In addition to the class effect of COX inhibition, there is evidence that indometacin has the ability to reduce cerebral blood flow not only through modulation of nitric oxide pathways but also via intracranial precapillary vasoconstriction. [ 19 ]

  8. Prostaglandin inhibitors - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_inhibitors

    Prostaglandin inhibitors are drugs that inhibit the synthesis of prostaglandin in human body. [1] There are various types of prostaglandins responsible for different physiological reactions such as maintaining the blood flow in stomach and kidney, regulating the contraction of involuntary muscles and blood vessels, and act as a mediator of inflammation and pain.

  9. Popular asthma drug Singulair could be linked to mental ... - AOL

    www.aol.com/popular-asthma-drug-singulair-could...

    If you or someone you know is struggling with suicidal thoughts, you can call the U.S. National Suicide Prevention Lifeline at 988 any time day or night, or chat online.. A new study on a drug ...