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Co-testing with a Pap test and HPV test is recommended because it decreases the rate of false-negatives. According to the National Cancer Institute, "The most common test detects DNA from several high-risk HPV types, but it cannot identify the types that are present.
Researchers at King’s College London said that screening women aged 24 to 49 who test negative for human papillomavirus (HPV) at five-year intervals prevented as many cancers as screening every ...
The highest-risk types are HPV 16 and 18; these are responsible for the vast majority of HPV-related cancers, including cancers of the cervix, vagina, vulva, penis, anus, and head and neck.
The negative predictive value is defined as: = + = where a "true negative" is the event that the test makes a negative prediction, and the subject has a negative result under the gold standard, and a "false negative" is the event that the test makes a negative prediction, and the subject has a positive result under the gold standard.
The Pap test can be used as a screening test, but produces a false negative in up to 50% of cases of cervical cancer. [56] [57] Other concerns is the cost of doing Pap tests, which make them unaffordable in many areas of the world. [58] Confirmation of the diagnosis of cervical cancer or precancer requires a biopsy of the cervix.
A negative home HPV test counts as a negative cervical cancer screening, allowing most people to avoid a clinic visit altogether; one less thing that requires scheduling, waiting at the office and ...
HPV disease is the leading cause of cervical cancer, therefore making the HPV vaccine the primary prevention measure for the cancer. Screening with the Papanicolaou (Pap) test is consequently the second measure of prevention. [27] The test identifies cells that are precancerous, and are often credited for the reduced mortality. [28]
Women and people with cervixes should have the option to use a self-swab human papillomavirus (HPV) test as part of a cervical cancer screen, the United States Preventative Services Task Force ...