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Thyroglossal cyst with papillary excrescences (magnified at right), where microscopy showed papillary thyroid cancer. Rarely (in less than 1% of cases), cancer may be present in a thyroglossal duct cyst. [6] These tumors are generally papillary thyroid carcinomas, [6] arising from the ectopic thyroid tissue within the cyst. [7] [8]
Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [ 1 ] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ .
Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, Hashimoto's disease, and autoimmune thyroiditis is an autoimmune disease in which the thyroid gland is gradually destroyed. [7] [1] Early on, symptoms may not be noticed. [3] Over time, the thyroid may enlarge, forming a painless goiter. [3]
Difficulty or pain with swallowing is called dysphagia, and it affects up to 15% or more of the population at some point in their lives.
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
Low levels of thyroid hormones can lead to symptoms including fatigue, weight gain, cold intolerance, dry, flakey skin, loss of hair and inability to concentrate.
Patients may present with symptoms of hypothyroidism and hypoparathyroidism as the gland is replaced by Fibrous tissues . Physical examination reveals a hard "woody" thyroid gland with fixation to surrounding tissue. [4] The diagnosis needs to be confirmed by open thyroid biopsy because the firm and Fibrous nature of the gland renders FNAB ...
Thyroid-like masses can also be seen in close relation along the duct. Enclosed vesicles and cysts can also be seen while studying the tissue of the duct. A persistent thyroglossal duct in a rabbit showed resemblance to the layout of the alimentary canal ; with its external fibrous connective tissue, muscular layers, submucosal glands, and ...
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