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  2. Lidocaine - Wikipedia

    en.wikipedia.org/wiki/Lidocaine

    Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]

  3. Bupivacaine - Wikipedia

    en.wikipedia.org/wiki/Bupivacaine

    Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease sensation in a specific small area. [5] In nerve blocks, it is injected around a nerve that supplies the area, or into the spinal canal's epidural space. [5] It is available mixed with a small amount of epinephrine to increase the duration of its ...

  4. Dental anesthesia - Wikipedia

    en.wikipedia.org/wiki/Dental_anesthesia

    Local anesthetic injections are given in specific areas of the mouth, rather than the whole body. Although several different medications are available, the most commonly used local anesthetic to prevent pain in the area around a tooth is lidocaine (also called xylocaine or lignocaine). Lidocaine's half-life in the body is about 1.5–2 hours. [2]

  5. Guys: Looking for a "Downstairs" Numbing Cream? Here's ... - AOL

    www.aol.com/guys-looking-downstairs-numbing...

    Compared to lidocaine cream, delay sprays with lidocaine tend to be faster-acting and easier to apply. This can make a spray a great option if you need a topical treatment that can be applied ...

  6. Chloroprocaine - Wikipedia

    en.wikipedia.org/wiki/Chloroprocaine

    Amide-linked local anesthetic agents, such as lidocaine and bupivacaine, can become "trapped" in their ionized forms on the fetal side of the placenta, so their net transfer across the placenta is increased. An ester-linked local anesthetic agent, such as 2-chloroprocaine, is rapidly metabolized, and placental transfer is limited.

  7. List of local anesthetics - Wikipedia

    en.wikipedia.org/wiki/List_of_local_anesthetics

    lidocaine [12] [13] (lignocaine) Xylocaine 1943 (Nils Löfgren and Bengt Lundqvist) 1947 (Torsten Gordh) mepivacaine: Carbocaine, Polocaine 1956 (Ekenstam and Egner) 1957 (Dhuner) meprylcaine: Epirocain metabutoxycaine: nitracaine: Ester- Aminobenzoic orthocaine: oxetacaine (oxethazaine) oxybuprocaine: benoxinate, Novesine Paraethoxycaine [14 ...

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    mail.aol.com

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  9. Myofascial trigger point - Wikipedia

    en.wikipedia.org/wiki/Myofascial_trigger_point

    A mixture of 1 part 2% lidocaine with 3 parts 0.5% bupivacaine provides 0.5% lidocaine and 0.375% bupivacaine. This has the advantages of immediate anesthesia with lidocaine during injection to minimize injection pain while providing a longer duration of action with a lowered concentration of bupivacaine. [citation needed]