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When examining cytologic specimens, a diagnosis of ASC-US is given if squamous cells are suspicious for low-grade squamous intraepithelial lesion (LSIL) but do not fulfill the criteria. This may be due to limitations in the quality of the specimen, or because the abnormalities in the cells are milder than that seen in LSIL. [6]
Because of this, LSIL results can be managed with a simple "watch and wait" philosophy. However, because there is a 12–16% chance of progression to more severe dysplasia, the physician may want to follow the results more aggressively by performing a colposcopy with biopsy . [ 7 ]
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
As a result, many people are exposed to much higher levels than ever before. It is important to understand what impact this has on human health,” he added. ... Because cancer cells take up more ...
The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
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Low blood pressure Let a healthcare professional know if you have any of these conditions or regularly experience angina-like chest pain. They may be able to recommend an alternative hair loss ...