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Clinical trials using repurposed, generally safe, existing drugs for hospitalized COVID-19 people may take less time and have lower overall costs to obtain endpoints proving safety (absence of serious side effects) and post-infection efficacy, and can rapidly access existing drug supply chains for manufacturing and worldwide distribution.
In March 2022, the BBC wrote, "There are now many drugs that target the virus or our body in different ways: anti-inflammatory drugs that stop our immune system overreacting with deadly consequences, anti-viral drugs that make it harder for the coronavirus to replicate inside the body and antibody therapies that mimic our own immune system to ...
[11] [12] Safety, efficacy, and clinical endpoints may vary, including the definition of side effects, infection or amount of transmission, and whether the vaccine prevents moderate or severe infection. [13] [14] [15] A clinical trial design in progress may adopt an "adaptive design". If accumulating data provide insights about the treatment ...
How COVID‑19 vaccines work. The video shows the process of vaccination, from injection with RNA or viral vector vaccines, to uptake and translation, and on to immune system stimulation and effect. Part of a series on the COVID-19 pandemic Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom. COVID-19 (disease) SARS-CoV-2 (virus) Cases Deaths ...
The vaccine can also have rare allergic side effects. Which COVID vaccine is better? The COVID vaccine that's best for you comes down to personal preference and what your health care provider ...
You might experience some side effects from the COVID vaccine—but they’re usually not much to worry about. The most common one is a sore arm or mild redness or swelling at the injection site ...
Anaphylaxis and other allergic reactions are known side effects of the Oxford–AstraZeneca COVID-19 vaccine. [1] [71] The European Medicines Agency (EMA) has assessed 41 cases of anaphylaxis from around 5 million vaccinations in the United Kingdom. [71] [72] Capillary leak syndrome is a possible side effect of the vaccine. [65]
In the original clinical trials for Pfizer-BioNTech's COVID-19 vaccine, for example, less than half of study participants reported side effects, but the shot worked well for the vast majority of ...
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