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Osteoarthritis most often occurs in the hands (at the ends of the fingers and thumbs), neck, lower back, knees, and hips. The main symptom is pain , causing loss of ability and often stiffness. The pain is typically made worse by prolonged activity and relieved by rest.
The treatments may include joint replacement surgery for severely damaged joints, immunosuppressants for immune system dysfunction, antibiotics when an infection is the cause, and discontinuing medication when an allergic reaction is the cause. When treating the primary cause, pain management may still play a role in treatment.
Osteoarthritis typically affects the weight-bearing joints, such as the back, knee and hip. Unlike rheumatoid arthritis, osteoarthritis is most commonly a disease of the elderly. The strongest predictor of osteoarthritis is increased age, likely due to the declining ability of chondrocytes to maintain the structural integrity of cartilage. [69]
It is not always certain why arthritis of the knee develops. [citation needed] The knee may become affected by almost any form of arthritis, including those related to mechanical damage of the structures of the knee (osteoarthritis, and post-traumatic arthritis), various autoimmune forms of arthritis (including; rheumatoid arthritis, juvenile arthritis, and SLE-related arthritis, psoriatic ...
In the early 1900s, dysfunction of the sacroiliac joint was a common diagnosis associated with low back and sciatic nerve pain. [18] However, research by Danforth and Wilson in 1925 concluded that the sacroiliac joint could not cause sciatic nerve pain because the joint does not have a canal in which the nerves can be entrapped against the ...
Radiculopathy, a nerve disorder brought on by pressure or irritation of a nerve at its root (i.e., near the spine) often resulting from degeneration of a spinal disc, joint degeneration, or osteoarthritis, among other causes; Pain in the groin, called anterior hip pain, is most often the result of osteoarthritis, osteonecrosis, occult fracture ...
Both big and small joints are affected, mainly lower limb joints like the metatarsophalangeal joints, ankles, and knees. Shoulder and hip arthritis is less common and is typically linked to spondylitis and sacroiliitis. [7] It does not cause joint deformities, but it is typically migratory, transitory, and recurrent. [8]
A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).