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The elimination half-life of testosterone in the blood or by intravenous injection is only about 10 minutes. [ 8 ] [ 33 ] Conversely, testosterone and testosterone esters in oil solution or crystalline aqueous suspension administered by intramuscular or subcutaneous injection have much longer half-lives, in the range of days to months, due to ...
Testosterone propionate is administered in oil via intramuscular injection. [1] [2] It has a relatively short elimination half-life and mean residence time of 2 days and 4 days, respectively. [1] [2] As such, it has a short duration of action and must be administered two to three times per week. [16]
For reference, testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days and requires frequent administration of approximately once per week. [21] Large fluctuations in testosterone levels result with it, with levels initially being elevated and supraphysiological. [21]
Testosterone undecanoate has a very long elimination half-life and mean residence time when given as a depot intramuscular injection. [27] [7] [8] Its elimination half-life is 20.9 days and its mean residence time is 34.9 days in tea seed oil, while its elimination half-life is 33.9 days and its mean residence time is 36.0 days in castor oil.
Pharmacokinetics of testosterone esters Testosterone ester Form Route T max Tooltip Time to peak levels t 1/2 Tooltip Elimination half-life MRT Tooltip Mean residence time; Testosterone undecanoate: Oil-filled capsules: Oral? 1.6 hours: 3.7 hours Testosterone propionate: Oil solution: Intramuscular injection? 0.8 days: 1.5 days Testosterone ...
“Women in their mid-40s and 50s have half the testosterone that we had in our 20s.” ... “About 10 to 20 percent of men will have low testosterone in their life, and they have at least 11 FDA ...
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