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<70 <1.8 Optimal LDL cholesterol, corresponding to lower rates of progression, promoted as a target option for those known to clearly have advanced symptomatic cardiovascular disease <100 <2.6 Optimal LDL cholesterol, corresponding to lower, but not zero, rates for symptomatic cardiovascular disease events 100 to 129 2.6 to 3.3
Remnant cholesterol has about twice the association with ischemic heart disease as LDL cholesterol. [14] Although remnant cholesterol tends to be higher in people who are overweight (high body mass index ), normal-weight persons with high remnant cholesterol tend to have a higher risk of myocardial infarction.
Levels of LDL or non-HDL cholesterol both predict future coronary heart disease; which is the better predictor is disputed. [39] High levels of small dense LDL may be particularly adverse, although measurement of small dense LDL is not advocated for risk prediction. [39] In the past, LDL and VLDL levels were rarely measured directly due to cost.
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The goal of maintaining optimal lipid levels throughout life is to keep the concentration of circulating LDL and other apo B–containing lipoproteins low to minimize the number of particles that become retained in the arterial wall and thereby minimize the rate of progression of atherosclerotic plaques.
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