Search results
Results from the WOW.Com Content Network
The direct Coombs test is used to test for autoimmune hemolytic anemia, a condition where the immune system breaks down red blood cells, leading to anemia. The direct Coombs test is used to detect antibodies or complement proteins attached to the surface of red blood cells. To perform the test, a blood sample is taken and the red blood cells ...
It detects antibodies bound to the surface of red blood cells in vivo. The red blood cells (RBCs) are washed (removing the patient's own plasma) and then incubated with antihuman globulin (also known as "Coombs reagent"). If this produces agglutination of the RBCs, the direct Coombs test is positive. The indirect Coombs test is used in prenatal ...
Robert Royston Amos Coombs (9 January 1921 – 25 January 2006) [1] was a British immunologist, co-discoverer of the Coombs test (1945) used for detecting antibodies in various clinical scenarios, such as Rh disease and blood transfusion.
In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [61] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
A laboratory test, the direct Coombs test, is used to detect these antibodies or complement proteins that are bound to the surface of red blood cells; a blood sample is taken and the RBCs are washed (removing the patient's own plasma) and then incubated with antihuman globulin (also known as "Coombs reagent").
Traumatic hemolytic anemia [2]. Impact [2]; Macrovascular defects-prostheses [2]; Microvascular causes [2]. Disseminated intravascular hemolysis [2]; Thrombotic thrombocytopenic purpura [2]
Retrieved from "https://en.wikipedia.org/w/index.php?title=Direct_coombs_test&oldid=213133333"
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Help; Learn to edit; Community portal; Recent changes; Upload file