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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
Surviving T4 virus released from multicomplexes show no increase in mutation, indicating that MR of UV irradiated virus is an accurate process. [36] The bottom figure shows the survival curves for inactivation of virus T4 by the DNA damaging agent mitomycin C (MMC). In this case the survival curve for multicomplexes has no initial shoulder ...
The T4 rII system is an experimental system developed in the 1950s by Seymour Benzer for studying the substructure of the gene. The experimental system is based on genetic crosses of different mutant strains of bacteriophage T4 , a virus that infects the bacteria Escherichia coli .
The virus particles have a distinct shape; each virion has an icosahedral head that contains the viral genome, and is attached to a flexible tail by a connector protein. [2] The order encompasses a wide range of viruses, many containing genes of similar nucleotide sequence and function.
During assembly of the bacteriophage (phage) T4 virion, the structural proteins encoded by the phage genes interact with each other in a characteristic sequence. Maintaining an appropriate balance in the amounts of each of these structural proteins produced during viral infection appears to be critical for normal phage T4 morphogenesis. [4]
Bacteriophage T4 is a virus that infects the bacterium E. coli. Bacteriophage T4 genes are conventionally classified as early function genes or late function genes based on the time period in which their protein products are expressed during the course of bacteriophage infection.
The virus exits the host cell by lysis, and holin/endolysin/spanin proteins. Bacteria and archaea serve as the natural host. Transmission route is passive diffusion. [2] Although Myoviruses are in general lytic, lacking the genes required to become lysogenic, a number of temperate species are known.
Research Styles in Virus Studies in the Twentieth Century: Controversies and the Formation of Consensus. Doctoral Thesis, University of Limburg. (note that though this is a thesis, it is of sufficient general interest toward addressing issues in the history of bacteriophagy as to warrant inclusion in this list)