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Common side effects include menstrual disturbances such as absence of periods, abdominal pain, and headaches. [10] More serious side effects include bone loss, blood clots, allergic reactions, and liver problems. [10] Use is not recommended during pregnancy as it may harm the baby. [10]
Common side effects of EC/MPA include irregular menstrual periods which typically improves with time. [3] Other side effects include blood clots, headache, hair loss, depression, nausea, and breast pain. [3] [4] Use during pregnancy is not recommended. [2] Use during breastfeeding is likely safe. [5] It works mainly by preventing ovulation. [2]
Side effects of estradiol cypionate include breast tenderness, breast enlargement, nausea, headache, and fluid retention. [ 14 ] [ 8 ] Estradiol cypionate is an estrogen and hence is an agonist of the estrogen receptor , the biological target of estrogens like estradiol .
Other side effects include breast tenderness/pain, headache, and libido changes. [26] Some fluid retention can occur, but weight gain is minimal. [26] Local injection site reactions have also been reported in 15 to 35% of women. [26] Effects of CICs on coagulation and fibrinolysis are minimal and are not thought to be clinically relevant. [27]
Side effects of testosterone cypionate include virilization among others. [4] Diminished sperm production is a common side-effect of testosterone replacement therapy because of the decreased intra-testicular concentration of testosterone and suppression of the hypothalamic-pituitary-gonadal axis. [20]
“The way it should be done has to be down to the individual and their healthcare professional, to agree a way which it can work and only when side-effects can be safely managed.
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
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