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Rates of restenosis differ between devices (e.g., stent-grafts, balloon angioplasty, etc.) and location of procedure (i.e., centrally located in the heart, such as the coronary artery, or in peripheral vessels such as the popliteal artery in the leg, the pudendal artery in the pelvis, or the carotid artery in the neck).
Neointimal hyperplasia refers to proliferation and migration of vascular smooth muscle cells primarily in the tunica intima, resulting in the thickening of arterial walls and decreased arterial lumen space. [1] [2] Neointimal hyperplasia is the major cause of restenosis after percutaneous coronary interventions such as stenting or angioplasty. [1]
In the legs, bypass grafting is used to treat peripheral vascular disease, acute limb ischemia, aneurysms and trauma.While there are many anatomical arrangements for vascular bypass grafts in the lower extremities depending on the location of the disease, the principle is the same: to restore blood flow to an area without normal flow.
The most common treatments are medications and surgery to repair the damaged blood vessels in your brain. Valvular heart disease Heart valve problems may be treated with medications or surgery.
Stricture as a term is usually used when narrowing is caused by contraction of smooth muscle (e.g. achalasia, prinzmetal angina); stenosis is usually used when narrowing is caused by lesion that reduces the space of lumen (e.g. atherosclerosis). [4] The term coarctation is another synonym, [5] but is commonly used only in the context of aortic ...
Angioplasty, also known as balloon angioplasty and percutaneous transluminal angioplasty (PTA), is a minimally invasive endovascular procedure used to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclerosis.
The surgery is generally performed under general anaesthesia. The surgeon makes an incision in the upper leg, and a graft either man-made or the patient's vein is sewn to both ends of the artery. [20] The graft reroutes the blood flow around the blocked artery, allowing for adequate supply back to the parts of the leg.
Stents, which are specially manufactured expandable stainless steel mesh tubes, mounted on a balloon catheter, are the most commonly used device beyond the balloon catheter. When the stent/balloon device is positioned within the stenosis, the balloon is inflated which, in turn, expands the stent and the artery.