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The effect of the particle size on solubility constant can be quantified as follows: = + where *K A is the solubility constant for the solute particles with the molar surface area A, *K A→0 is the solubility constant for substance with molar surface area tending to zero (i.e., when the particles are large), γ is the surface tension ...
The solubility of a specific solute in a specific solvent is generally expressed as the concentration of a saturated solution of the two. [1] Any of the several ways of expressing concentration of solutions can be used, such as the mass, volume, or amount in moles of the solute for a specific mass, volume, or mole amount of the solvent or of the solution.
Particle-size analysis also helps the effectiveness of SAG Mills when crushing material. In the building industry, the particle size can directly affect the strength of the final material, as it observed for cement. [18] Two of the most used techniques used for the particle size characterization of minerals are sieving and laser diffraction.
As a result, the average size of the nanoparticles in the solution will grow, and the dispersion of sizes will decrease. Therefore, if a solution is left for a long time, in the extreme case of t → ∞ {\displaystyle t\rightarrow \infty } , its particles would evolve until they would finally form a single huge spherical particle to minimize ...
For many drugs, reducing the particle size reduces the dose needed to achieve the same therapeutic effect. The particle size reduction increases the specific surface area and the dissolution rate and does not affect solubility. The rate of dissolution may also be altered by choosing a suitable polymorph of a compound. Different polymorphs have ...
Particle size is a notion introduced for comparing dimensions of solid particles (), liquid particles (), or gaseous particles ().The notion of particle size applies to particles in colloids, in ecology, in granular material (whether airborne or not), and to particles that form a granular material (see also grain size).
The particle's Mean squared displacement from its original position is: =, where is the dimension of the particle's Brownian motion. For example, the diffusion of a molecule across a cell membrane 8 nm thick is 1-D diffusion because of the spherical symmetry; However, the diffusion of a molecule from the membrane to the center of a eukaryotic ...
In addition to the classification by particle size, dispersions can also be labeled by the combination of the dispersed phase and the medium phase that the particles are suspended in. Aerosols are liquids dispersed in a gas, sols are solids in liquids, emulsions are liquids dispersed in liquids (more specifically a dispersion of two immiscible ...