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Microvilli (sg.: microvillus) are microscopic cellular membrane protrusions that increase the surface area for diffusion and minimize any increase in volume, [1] and are involved in a wide variety of functions, including absorption, secretion, cellular adhesion, and mechanotransduction.
Microvilli on the apical surface increase its surface area. This facilitates transport of numerous small molecules into the enterocyte from the intestinal lumen . These include broken down proteins , fats , and sugars , as well as water, electrolytes , vitamins , and bile salts .
The terminal web is a filamentous structure found at the apical surface of epithelial cells that possess microvilli.It is composed primarily of actin filaments stabilized by spectrin, which also anchors the terminal web to the apical cell membrane.
Drawing showing the relationship between villi and microvilli of the small intestine. The luminal surface of the enterocytes have microvilli (1 micrometer long) while the cell layer itself is folded to form villi (0.5-1.6 millimeters long) and crypts. Both serve to increase the total absorption surface of the intestine.
Microvilli increase the surface area of a tissue, such as from their abundance on tissue protrusions such as intestinal villi. There is increasing evidence that membrane protrusions may act as platforms for the budding of extracellular vesicles .
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Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis , the outermost layer of the skin . Epithelial ( mesothelial ) tissues line the outer surfaces of many internal organs , the corresponding inner surfaces of body cavities , and the inner surfaces of ...