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  2. Amygdala - Wikipedia

    en.wikipedia.org/wiki/Amygdala

    Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.

  3. Limbic system - Wikipedia

    en.wikipedia.org/wiki/Limbic_system

    He postulated the limbic system as the brain's center of emotions, including the hippocampus and amygdala. Developing observations made by Papez, he hypothesized that the limbic system had evolved in early mammals to control fight-or-flight responses and react to both emotionally pleasurable and painful sensations.

  4. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Depression may be related to abnormalities in the circadian rhythm, [22] or biological clock. A well synchronized circadian rhythm is critical for maintaining optimal health. Adverse changes and alterations in the circadian rhythm have been associated with various neurological disorders and mood disorders including depression. [23]

  5. Human brain - Wikipedia

    en.wikipedia.org/wiki/Human_brain

    The brain is the central organ of the human nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sensory nervous system ...

  6. Striatum - Wikipedia

    en.wikipedia.org/wiki/Striatum

    The striatum (pl.: striata) or corpus striatum [5] is a cluster of interconnected nuclei that make up the largest structure of the subcortical basal ganglia. [6] The striatum is a critical component of the motor and reward systems; receives glutamatergic and dopaminergic inputs from different sources; and serves as the primary input to the rest of the basal ganglia.

  7. Brodmann area 25 - Wikipedia

    en.wikipedia.org/wiki/Brodmann_area_25

    This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxiety; the hippocampus, which plays an important role in memory formation; and some parts of the frontal cortex responsible for self ...

  8. Ventromedial prefrontal cortex - Wikipedia

    en.wikipedia.org/wiki/Ventromedial_prefrontal_cortex

    The ventromedial prefrontal cortex (vmPFC) is a part of the prefrontal cortex in the mammalian brain.The ventral medial prefrontal is located in the frontal lobe at the bottom of the cerebral hemispheres and is implicated in the processing of risk and fear, as it is critical in the regulation of amygdala activity in humans. [2]

  9. Medial forebrain bundle - Wikipedia

    en.wikipedia.org/wiki/Medial_forebrain_bundle

    The medial forebrain bundle may serve as a target in treating treatment-resistant depression. [8] Since the MFB connects areas of the brain which are involved with motivated behavior, mood regulation, and antidepressant response the stimulation of the MFB through deep brain stimulation could be an effective form of treatment. However, the ...