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  2. Chronic obstructive pulmonary disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_obstructive...

    Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...

  3. Multilevel modeling for repeated measures - Wikipedia

    en.wikipedia.org/wiki/Multilevel_Modeling_for...

    In multilevel modeling, an overall change function (e.g. linear, quadratic, cubic etc.) is fitted to the whole sample and, just as in multilevel modeling for clustered data, the slope and intercept may be allowed to vary. For example, in a study looking at income growth with age, individuals might be assumed to show linear improvement over time.

  4. Asthma-COPD overlap - Wikipedia

    en.wikipedia.org/wiki/Asthma-COPD_overlap

    ACO presents with symptoms of both asthma and COPD. [1] ACO presents in adulthood, usually after the age of 40 (after there has been significant tobacco smoke or other toxic fumes exposure), with symptoms of dyspnea (shortness of breath), exercise intolerance, sputum production, cough and episodes of symptomatic worsening known as exacerbations.

  5. ABI Solid Sequencing - Wikipedia

    en.wikipedia.org/wiki/ABI_Solid_Sequencing

    SOLiD (Sequencing by Oligonucleotide Ligation and Detection) is a next-generation DNA sequencing technology developed by Life Technologies and has been commercially available since 2006. This next generation technology generates 10 8 - 10 9 small sequence reads at one time.

  6. Alpha-1 antitrypsin deficiency - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_antitrypsin_deficiency

    Life expectancy among those who smoke is 50 years while among those who do not smoke it is almost normal. [3] The condition affects about 1 in 2,500 people of European descent. [1] Severe deficiency occurs in about 1 in 5,000. [5] In Asians it is uncommon. [1] About 3% of people with COPD are believed to have the condition. [5]

  7. Emphysema - Wikipedia

    en.wikipedia.org/wiki/Emphysema

    When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. [10] [11] Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality risk in tobacco smokers ...

  8. Lung cancer screening - Wikipedia

    en.wikipedia.org/wiki/Lung_cancer_screening

    The 2021 U.S. Preventive Services Task Force guidelines recommend annual screening for lung cancer with low-dose computed tomography in adults aged 50 to 80 years who have a 20 pack-year smoking history and currently smoke or have quit within the past 15 years. [6]

  9. Screening (medicine) - Wikipedia

    en.wikipedia.org/wiki/Screening_(medicine)

    Several types of screening exist: universal screening involves screening of all individuals in a certain category (for example, all children of a certain age). Case finding involves screening a smaller group of people based on the presence of risk factors (for example, because a family member has been diagnosed with a hereditary disease).