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Theophylline extended-release tablets in Japan. Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. [1] It is used to treat chronic obstructive pulmonary disease (COPD) and asthma. [2] Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine ...
The common side effects of Tedral include gastrointestinal disturbances, dizziness, headache and lightheadedness. [3] [4] [5] However, at high dose, it may lead to cardiac arrhythmias, hypertension, seizures or other serious cardiovascular and/or central nervous system adverse effects.
[9] [7] [10] A ratio of 5:1 theophylline to ephedrine is usually used in combinations of the drugs. [11] Later research found that the combination was no more effective for asthma than theophylline alone but produced more side effects. [9] [1] [12] [7]
This suggests that its antiasthmatic effects are mediated by another mechanism, perhaps its actions on phosphodiesterase. [1] From a pharmacokinetic point of view, doxofylline importantly differs from theophylline also because it lacks the ability to interfere with the cytochrome enzymes CYP1A2 , CYP2E1 and CYP3A4 , thus preventing significant ...
It was a combination of theophylline, ephedra, [1] and hydroxyzine, and taken by mouth. [ 2 ] [ 3 ] It is no longer manufactured in the US due to approval of ephedra being withdrawn by the FDA . [ citation needed ]
Turkey Cheese Ball. Even if you're not serving turkey this Thanksgiving doesn't mean you can't get in on the theme. Enter: this adorable cheeseball.We used carrots, pecans, pretzels, and bell ...
The beneficial effects of small alkyl groups on the heterocycle could be to twist the central ring away from exact coplanarity with the heterocyclic ring. There is a similar twist in cAMP and there is general agreement that high affinity PDE3 inhibitors should adopt an energetically favoured planar conformation that mimics the anti conformation ...
However, deprescribing may be considered if a patient experiences side effects like rapid heart rate, anxiety, or bone loss, or if their thyroid function tests normalize.” ...