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Janssen Pharmaceuticals was the first Western pharmaceutical company to set up a pharmaceutical factory in the People's Republic of China. [ 27 ] In 1976, Paul Janssen met Ma Haide (born George Shafik Hatem), a Lebanese-American doctor who had started working in China in 1933.
In 1961, Johnson & Johnson acquired Janssen Pharmaceuticals, which had been founded in 1953 by Belgian scientist Paul Janssen, [47] the inventor of Fentanyl. [48] In 1963, Philip B. Hofmann succeeded Robert Wood Johnson as chairman and CEO. He was the first non-Johnson family member to become chief executive.
Pharmaceutical therapies [ edit ] The company's major franchises in the pharmaceuticals segment include immunology , neuroscience , infectious disease and vaccines, oncology , cardiovascular and metabolism , and pulmonary hypertension .
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In 1985, Janssen Pharmaceutical became the first Western pharmaceutical company to establish a factory in China. [10] In 1995, together with Paul Lewi , he founded the Center for Molecular Design, where he and his team [ 11 ] used a supercomputer to search candidate molecules for potential AIDS treatments.
It was developed by Janssen Pharmaceuticals and licensed to NewVac LLC. [7] Preclinical studies show that quisinostat amplifies HDAC-repressed expression of E-cadherin, leading to a reversal of epithelial to mesenchymal transition in tumor cells. [7]
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