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A mediastinal tumor is a tumor in the mediastinum, the cavity that separates the lungs from the rest of the chest. It contains the heart , esophagus , trachea , thymus , and aorta . The most common mediastinal masses are thymoma (20% of mediastinal tumors), usually found in the anterior mediastinum, followed by neurogenic Timor (15–20% ...
The treatment for mediastinal nonseminomatous germ cell tumors should follow guidelines for poor-prognosis testicular cancer. Initial treatment with four courses of bleomycin, etoposide, and cisplatin, followed by surgical resection of any residual disease, is considered standard therapy.
Several methods of treatment are available, mainly consisting of careful drug therapy and surgery. [5] Glucocorticoids (such as prednisone or methylprednisolone) decrease the inflammatory response to tumor invasion and edema surrounding the tumor. [5] Glucocorticoids are most helpful if the tumor is steroid-responsive, such as lymphomas.
Consideration of surgery is recommended for Stage 1 limited-stage small cell lung cancer patient with a solitary nodule, no hilar or mediastinal involvement, absence of distant metastases, and no contraindications to surgery classified by the TNM staging system. [18] Surgery is normally followed by chemotherapy.
Secondary pleural malignancies include metastasis from distant primary tumors including breast, colon, ovarian, uterine and renal cell carcinoma among others; as well as certain sarcomas and pseudomyxoma peritonei. Treatment options for such advanced diseases are limited to systemic chemotherapy, radiation, and supportive care measures.
In 2022, Pascual was diagnosed with Stage 4 mediastinal paraganglioma, a rare form of cancer that spread to his lungs and bones, leaving him with a five-year survival estimate, according to his ...
Primary mediastinal B-cell lymphoma, abbreviated PMBL or PMBCL, is a rare type of lymphoma that forms in the mediastinum (the space in between the lungs) and predominantly affects young adults. [ 1 ] [ 2 ] [ 3 ]
Overall classification, also known as "staging", can help predict treatment options for patients. [14] Staging consists of three separate evaluations. The first is of the tumour/cancer itself ("T"). [14] The second is the extent to which adjacent lymph nodes are involved in the tumour/cancer's spread ("N"). [14]
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