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Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems.
The microbial food web is important because it is the direct target of the viral shunt pathway and all subsequent effects are based on how the viruses affect their microbial hosts. Infection of these microbes through lysis or latent infection have a direct impact of the nutrients recycled, availability, and export within the microbial loop ...
The viral eukaryogenesis hypothesis posits that eukaryotes are composed of three ancestral elements: a viral component that became the modern nucleus; a prokaryotic cell (an archaeon according to the eocyte hypothesis) which donated the cytoplasm and cell membrane of modern cells; and another prokaryotic cell (here bacterium) that, by endocytosis, became the modern mitochondrion or chloroplast.
Life-cycle of a typical virus (left to right); following infection of a cell by a single virus, hundreds of offspring are released. When a virus infects a cell, the virus forces it to make thousands more viruses. It does this by making the cell copy the virus's DNA or RNA, making viral proteins, which all assemble to form new virus particles. [37]
Viral phylodynamics is the study of how epidemiological, immunological, and evolutionary processes act and potentially interact to shape viral phylogenies. [1] Since the term was coined in 2004, research on viral phylodynamics has focused on transmission dynamics in an effort to shed light on how these dynamics impact viral genetic variation.
A freshwater aquatic food web. The blue arrows show a complete food chain (algae → daphnia → gizzard shad → largemouth bass → great blue heron). A food web is the natural interconnection of food chains and a graphical representation of what-eats-what in an ecological community.
If a model makes predictions that are out of line with observed results and the mathematics is correct, the initial assumptions must change to make the model useful. [ 13 ] Rectangular and stationary age distribution , i.e., everybody in the population lives to age L and then dies, and for each age (up to L ) there is the same number of people ...
Entry, or penetration, is the second step in viral replication. This step is characterized by the virus passing through the plasma membrane of the host cell. The most common way a virus gains entry to the host cell is by receptor-mediated endocytosis, which comes at no energy cost to the virus, only the host cell. Receptor-mediated endocytosis ...