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It is the only drug authorised by the EMA to treat the whole disease in adults, and by the FDA to treat patients who have cataplexy with the indication to be used for combating excessive daytime sleepiness. [4] [20] This drug helps to normalise sleep architecture and inhibits the intrusion REM sleep elements like paralysis during the day. [4]
Catalepsy is a symptom of certain nervous disorders or conditions such as Parkinson's disease and epilepsy.It is also a characteristic symptom of cocaine withdrawal, as well as one of the features of catatonia.
Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
The reality is, roughly 21 million adults in the U.S. experienced a major depressive episode in 2021. There’s good news, though. ... social anxiety and cataplexy, which can cause sudden muscle ...
Night terror, also called sleep terror, is a sleep disorder causing feelings of panic or dread and typically occurring during the first hours of stage 3–4 non-rapid eye movement (NREM) sleep [1] and lasting for 1 to 10 minutes. [2]
A Mass General Brigham emergency care doctor shares step-by-step guidance on how to administer the Heimlich maneuver to adults, children and yourself in a choking event.
Pitolisant is indicated in adults for the treatment of narcolepsy. [3] [4] Narcolepsy is a chronic sleep disorder that causes overwhelming daytime drowsiness. [4] Pitolisant is also indicated to improve alertness and reduce excessive daytime sleepiness in adults with obstructive sleep apnea. [5] [12]
Sleep apnea is the second most frequent cause of secondary hypersomnia, affecting up to 4% of middle-aged adults, mostly men. Upper airway resistance syndrome (UARS) is a clinical variant of sleep apnea that can also cause hypersomnia. [8] Just as other sleep disorders (like narcolepsy) can coexist with sleep apnea, the same is true for UARS.