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Thus they serve as immunomodulators in immunotherapy (therapy that makes use of immune responses), which can be helpful in treating cancer (where targeted therapy often relies on the immune system being used to attack cancer cells) and in treating autoimmune diseases (in which the immune system attacks the self), such as some kinds of arthritis ...
Anakinra, sold under the brand name Kineret, is a biopharmaceutical medication used to treat rheumatoid arthritis, cryopyrin-associated periodic syndromes, familial Mediterranean fever, and Still's disease. [3] It is a slightly modified recombinant version of the human interleukin 1 receptor antagonist protein. [3]
A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...
374 11839 Ensembl ENSG00000109321 ENSMUSG00000029378 UniProt P15514 P31955 RefSeq (mRNA) NM_001657 NM_009704 RefSeq (protein) NP_001648 NP_033834 Location (UCSC) Chr 4: 74.45 – 74.46 Mb Chr 5: 91.29 – 91.3 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Amphiregulin, also known as AREG, is a protein synthesized as a transmembrane glycoprotein with 252 aminoacids and it is encoded ...
It is used to treat cancer, autoimmune diseases, and ectopic pregnancies. [4] Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, gestational trophoblastic disease, and osteosarcoma. [4] Types of autoimmune diseases it is used for include psoriasis, rheumatoid arthritis, and Crohn's disease. [4]
rheumatoid arthritis, Crohn's disease, plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, hemolytic disease of the newborn: Adecatumumab [9] mab: human: EpCAM: prostate and breast cancer: Aducanumab [10] Aduhelm: mab: human: Amyloid beta: Y [11] Alzheimer's disease: Afasevikumab [12] mab: human: IL-17A ...
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