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Increases sympathomimetic effect of ephedra [3] Feverfew: featherfew Tanacetum parthenium: Aspirin Additive effect [3] Garlic: Allium sativum: Warfarin Additive effect Ginger: Zingiber officinale: Warfarin Additive effect, causes iris bleeding [3] Ginkgo gingko Ginkgo biloba: Aspirin, warfarin, ticlopidine, clopidogrel, dipyridamole, garlic ...
Warfarin is indicated for the prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism; [9] prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation and/or cardiac valve replacement; [9] and reduction in the risk of death, recurrent myocardial infarction, and thromboembolic events such as stroke or systemic embolization after ...
Furanocoumarins have other biological effects as well. For example, in humans, bergamottin and 6',7'-dihydroxybergamottin are responsible for the " grapefruit juice effect ", in which these furanocoumarins affect certain P450 liver and gut enzymes, such as the inhibition of CYP3A4 which either activates or deactivates many drugs, thus leading ...
The effects last because grapefruit-mediated inhibition of drug metabolizing enzymes, like CYP3A4, is irreversible; [30] that is, once the grapefruit has "broken" the enzyme, the intestinal cells must produce more of the enzyme to restore their capacity to metabolize drugs that the enzyme is used to metabolize. [19]
Of the anticoagulants, warfarin (and related coumarins) and heparin are the most commonly used. Warfarin affects the vitamin K-dependent clotting factors (II, VII, IX, X) and protein C and protein S, whereas heparin and related compounds increase the action of antithrombin on thrombin and factor Xa.
They are categorised as "first-generation" anticoagulants, and have similar effects as warfarin. They have been largely superseded by second-generation anticoagulants because warfarin-resistant rodents have become more common. [6] Anisindione, fluindione, and phenindione are oral anticoagulant medicines with actions similar to warfarin. However ...
An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.
Mangifera odorata, commonly known as kwini (also spelled kuini, kuweni, kuwini, etc.), [4] huani, [5] or Saipan mango, [2] is a species of plant with edible fruit in the family Anacardiaceae. [1] It is similar to the related mango but is characterized by a strong turpentine -like smell on the skin and fibrous flesh.