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The causes of leg cramps at night can range from nutrient deficiency to tough workouts. Here, experts break down how to prevent and get rid of leg cramps.
Up to 80% of athletes using statins experience significant adverse muscular effects, including cramps; [21] the rate appears to be approximately 10–25% in a typical statin-using population. [ 22 ] [ 23 ] In some cases, adverse effects disappear after switching to a different statin; however, they should not be ignored if they persist, as they ...
But the symptoms, when they do occur, tend to be mild and it’s not clear that statins are the reason. As with myalgia, trying another statin or tweaking the dosage often clears the fog.
SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.
Muscle pain and other symptoms often cause patients to stop taking a statin. [87] This is known as statin intolerance. A 2021 double-blind multiple crossover randomized controlled trial (RCT) in statin-intolerant patients found that adverse effects, including muscle pain, were similar between atorvastatin and placebo. [88]
Part of the power of statins lies in the fact that they cause few side effects. “Generally, about 90 out of 100 people have no trouble with a stain,” says Dr. Blumenthal.
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