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Metformin reduces intestinal absorption of vitamin B12 and also serum vitamin B12 concentration, thus patients are recommended to monitor B12 deficiency with complete blood count. [36] Regarding breastfeeding, metformin does not show obvious association with adverse outcomes. [ 37 ]
Experts say that metformin and insulin can also be used together to help women with type 2 diabetes and gestational diabetes manage blood glucose levels during pregnancy. Metformin is just as safe ...
Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [2] Gestational diabetes generally results in few symptoms; [2] however, obesity increases the rate of pre-eclampsia, cesarean sections, and embryo macrosomia, as well as gestational diabetes. [2]
A large number of pregnant women have been found to have low levels of vitamin B12, but supplementation has not yet been shown to improve pregnancy outcome or the health of the newborn. [ 12 ] Long-chain polyunsaturated fatty acids, specifically docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are beneficial for fetal development.
Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication or starting vitamin B12 supplementation appears to reverse this. Seek medical advice if ...
Left untreated, vitamin B12 deficiencies can lead to serious health problems including neurological problems and anemia. [88] Although more research is needed to understand the mechanisms of this association, it is suggested that people who take metformin monitor their vitamin B12 levels and if low, begin supplementation. [87]
A study on 702 women found that the clinical pregnancy rate for those using metformin versus a placebo group was significantly increased. shironosov / iStock. 7. Helps Manage Gestational Diabetes.
In some cases, pregnant women with diabetes may be encouraged to express and store their colostrum during pregnancy, in case their blood sugar is too low for feeding the baby breast milk after birth. [18] There is no evidence on the safety or potential benefits when pregnant women with diabetes express and store breast milk prior to the baby's ...