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Experts say that metformin and insulin can also be used together to help women with type 2 diabetes and gestational diabetes manage blood glucose levels during pregnancy. Metformin is just as safe ...
Metformin reduces intestinal absorption of vitamin B12 and also serum vitamin B12 concentration, thus patients are recommended to monitor B12 deficiency with complete blood count. [36] Regarding breastfeeding, metformin does not show obvious association with adverse outcomes. [ 37 ]
Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [2] Gestational diabetes generally results in few symptoms; [2] however, obesity increases the rate of pre-eclampsia, cesarean sections, and embryo macrosomia, as well as gestational diabetes. [2]
Left untreated, vitamin B12 deficiencies can lead to serious health problems including neurological problems and anemia. [88] Although more research is needed to understand the mechanisms of this association, it is suggested that people who take metformin monitor their vitamin B12 levels and if low, begin supplementation. [87]
Metformin shows may also help reduce the severity of diseases relating to insulin and glucose levels. This includes PCOS, certain tumor-related cancers, gestational diabetes and age-related diseases.
Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication or starting vitamin B12 supplementation appears to reverse this. Seek medical advice if ...
Reduced serum levels of vitamin B 12 occur in up to 30% of people taking long-term anti-diabetic metformin. [102] [103] Deficiency does not develop if dietary intake of vitamin B 12 is adequate or prophylactic B 12 supplementation is given. If the deficiency is detected, metformin can be continued while the deficiency is corrected with B 12 ...
In some cases, pregnant women with diabetes may be encouraged to express and store their colostrum during pregnancy, in case their blood sugar is too low for feeding the baby breast milk after birth. [18] There is no evidence on the safety or potential benefits when pregnant women with diabetes express and store breast milk prior to the baby's ...