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Weight loss can improve fertility problems for people with obesity. For example, several studies suggest that women with excess weight or obesity take longer to conceive and have a higher ...
A weight-loss study was carried out of 13 individuals over a 6-month period. [45] 12 of the 13 previously infertile subjects restored ovulation whilst 11 subjects were able to conceive after the programme had ended. This study demonstrates weight loss to be the primary source of treatment for obesity and fertility problems before ART.
The routine use of VLCDs is not recommended due to safety concerns, but this approach can be used under medical supervision if there is a clinical rationale for rapid weight loss in obese individuals, as part of a "multi-component weight management strategy" with continuous support and for a maximum of 12 weeks, according to the NICE 2014 guidelines. [12]
A different study corroborates these results and suggests a physiological dose (800 μg) of 5-methyltetrahydrofolate can bypass MTHFR C677T and A1298C isoforms in couples with fertility problems. [16] This treatment with 5-MTHF also avoids un-metabolized folic acid syndrome, which can occur with folic acid intakes of 5 mg per day. [16]
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ST. LOUIS, MO (KTVI) – If you want to get pregnant, you might want to think twice about popping a painkiller. New research shows it could impact a woman's fertility. Dr. Emily Jungheim, a ...
For those who after weight loss still are anovulatory or for anovulatory lean women, ovulation induction to reverse the anovulation is the principal treatment used to help infertility in PCOS. Letrozole and Clomiphene citrate are the first-line treatment in subfertile anovulatory patients with PCOS. [ 12 ]
Mild calorie restriction may be beneficial for pregnant women to reduce weight gain (without weight loss) and reduce perinatal risks for both the mother and child. [11] [12] For overweight or obese individuals, calorie restriction may improve health through weight loss, although a gradual weight regain of 1–2 kg (2.2–4.4 lb) per year may occur.