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Alcohol flush reaction is a condition that is experienced more frequently by people of East Asian descent, giving rise to names such as "Asian flush" or "Asian glow". [citation needed] Genotype frequency distribution of ALDH2 (rs671).
Alcohol-induced asthma reactions among Asians has been most thoroughly studied in those of native Japanese descent. In such individuals, the ingestion of virtually any alcoholic beverage or pure ethanol and, in some cases, the smelling of ethanol fumes may be followed, typically within 1–30 minutes, by one or more of the following symptoms: an alcohol flush reaction (i.e. the "Asian flush ...
Alcohol metabolism. ALDH1 is an isozyme of aldehyde dehydrogenase.A structural mutation in the gene of ALDH1, commonly found in East Asians, results in low levels of functional ALDH1 enzyme and thus, higher blood acetaldehyde levels.
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About 50% of people of Northeast Asian descent have a dominant mutation in their acetaldehyde dehydrogenase gene, [6] making this enzyme less effective, which causes the alcohol flush reaction, also known as Asian flush syndrome.
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The high concentration of acetaldehyde causes the alcohol flush reaction, colloquially known as the "Asian Flush". Since the alcohol flush reaction is highly uncomfortable and the possibility of hangovers is immediate and severe, people with this gene variant are less likely to become alcoholics. [16] [17]
Drink plenty of water to help flush uric acid out of your body. Get regular exercise . Ask your healthcare provider about healthy weight loss strategies if you have overweight or obesity.