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For both males and females, the initial aim for treatment is the development of the secondary sexual characteristics normally seen at puberty. [ 3 ] [ 39 ] [ 34 ] [ 35 ] [ 40 ] Once this has been achieved, continued hormone replacement therapy is required for both males and females to maintain sexual function, bone health, libido and general ...
Puberty is considered delayed when the child has not begun puberty when two standard deviations or about 95% of children from similar backgrounds have. [7] [8] [9]In North American girls, puberty is considered delayed when breast development has not begun by age 13, when they have not started menstruating by age 15, [2] and when there is no increased growth rate. [8]
Puberty blockers are commonly used to delay puberty in children with precocious puberty, a condition that activates the hypothalamic-pituitary-gonadal axis prematurely and initiates puberty at an inappropriate age. [30] The main goal of treatment is to preserve children's adult height potential. [31]
“Puberty blockers are sort of like a man-made hormone analogue, and basically what they do is fool the brain into not sending messages to the ovaries and testes to secrete hormones,” said Dr ...
Hypogonadism is often discovered during the evaluation of delayed puberty, but ordinary delay, which eventually results in normal pubertal development, wherein reproductive function is termed constitutional delay. It may be discovered during an infertility evaluation in either men or women. [8]
Aromatase deficiency is a rare condition characterized by extremely low levels or complete absence of the enzyme aromatase activity in the body. [2] It is an autosomal recessive disease resulting from various mutations of gene CYP19 (P450arom) which can lead to ambiguous genitalia and delayed puberty in females, continued linear growth into adulthood and osteoporosis in males and virilization ...
Hypergonadotropic hypogonadism (HH), also known as primary or peripheral/gonadal hypogonadism or primary gonadal failure, is a condition which is characterized by hypogonadism which is due to an impaired response of the gonads to the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and in turn a lack of sex steroid production. [1]
Hanlon blocked the state from prohibiting minors’ access to hormone therapies and puberty blockers but allowed the law’s prohibition on gender-affirming surgeries to take effect.