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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity. [4] [5]
Set point theory can be construed as implying weight regulation in a wide or tight range around the set point, in a symmetric or in an asymmetric manner (i.e. treating weight gain and loss either the same or differently), and may apply to regulation of body fat levels specifically (in a multi-compartment model) or to overall body weight. Set ...
Researchers suggest a few reasons for this: One is the "set point" theory, which posits that your body will fight to maintain the same weight through metabolic adaptations. These adaptations ...
The interaction between the genetic factors and environmental stimulus is what results in the disease phenotype. [19] There may be significant public health benefits in using gene by environment interactions to prevent or cure disease. [20] An individual's response to a drug can result from various gene by environment interactions. [19]
A study presented at the Digestive Disease Week 2024 conference examined 84 people with obesity or other weight management issues in order to investigate how genetics plays a role in weight loss ...
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On average obese people have a greater energy expenditure than normal weight or thin people and actually have higher basal metabolic rates. [45] [46] This is because it takes more energy to maintain an increased body mass. [47] Obese people also underreport how much food they consume compared to those of normal weight. [48]
Gene–environment correlations (or rGE) is correlation of two traits, e.g. height and weight, which would mean that when one changes, so does the other. Gene–environment correlations can arise by both causal and non-causal mechanisms. [1] Of principal interest are those causal mechanisms which indicate genetic control over environmental ...