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The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1] People with narcolepsy tend to sleep about the same number of hours per day as people without it, but the quality of sleep is typically compromised. [1]
Cataplexy without narcolepsy is rare and the cause is unknown. The term cataplexy originates from the Greek κατά ( kata , meaning "down"), and πλῆξις ( plēxis , meaning "strike") [ 4 ] and it was first used around 1880 in German physiology literature to describe the phenomenon of tonic immobility also known as " playing possum " (in ...
Pediatric narcolepsy cases are cases when patients are diagnosed or experience symptoms onset for narcolepsy before the age of 18. Of patients who obtain a formal diagnosis for narcolepsy, more than 50% report first experiencing symptoms of narcolepsy more than 10 years before their formal diagnosis, with an average age of symptom onset being at age 15 and symptom onset most likely to occur ...
[46] Family cases are frequent, in a range from 25% to 66% without any clear mode of inheritance." [26] IH has long been considered a rare disease, believed to be 10 times less frequent than narcolepsy. [26] The prevalence of narcolepsy (with cataplexy) is estimated between 1/3,300 and 1/5,000. [47]
Laughter-induced syncope should not be confused with cataplexy, a sudden loss of muscle tone triggered by strong emotions, particularly laughter. Unlike syncope, there is no loss of consciousness in cataplexy, which affects 65-75% of patients with narcolepsy. [2]
Narcolepsy (with and without cataplexy) Idiopathic hypersomnia; ... and symptoms similar to those of idiopathic hypersomnia can be seen within 6–18 months following ...
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