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In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by which a cell decreases the production and quantities of its cellular components, such as RNA and proteins, in response to an external stimulus.
Up-regulation is a process which occurs within a cell triggered by a signal (originating internal or external to the cell), which results in increased expression of one or more genes and as a result the proteins encoded by those genes. Conversely, down-regulation is a process resulting in decreased gene and corresponding protein expression.
Neural top–down control of physiology concerns the direct regulation by the brain of physiological functions (in addition to smooth muscle and glandular ones). Cellular functions include the immune system’s production of T-lymphocytes and antibodies, and nonimmune related homeostatic functions such as liver gluconeogenesis, sodium reabsorption, osmoregulation, and brown adipose tissue ...
Down-regulation of BRCA1 due to mutation occurs in about 3% of breast cancers. [25] Down-regulation of BRCA1 due to methylation of its promoter occurs in about 14% of breast cancers. [26] However, increased expression of miR-182 down-regulates BRCA1 mRNA and protein expression, [27] and increased miR-182 is found in 80% of breast cancers. [28]
Related: Ozempic vs Metformin For Weight Loss. Related: Does Muscle Weigh More than Fat? Breaking Down the Numbers. This article originally appeared on ForHers.com and was syndicated by MediaFeed.org.
Innovation and regulation are mutually exclusive in the world of crypto - and in the aftermath of the FTX collapse, getting the balance right is key. Innovation vs Regulation [Video] Skip to main ...
Gene regulatory pathway. In genetics, a regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences, which encode regulatory genes, are often at the five prime end (5') to the start site of transcription of the gene they regulate.
Tokens such as XRP and ADA jumped Friday on news that SEC chairman Gary Gensler planned to step down once Trump returns to the White House. Cryptos targeted by regulation are soaring on SEC chair ...