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[5] [6] [7] Promethazine is taken by mouth (oral), as a rectal suppository, or by injection into a muscle (IM). [4] Common side effects of promethazine include confusion and sleepiness; [4] consumption of alcohol or other sedatives can make these symptoms worse. [4] It is unclear if use of promethazine during pregnancy or breastfeeding is safe ...
Patients under chlorpromazine showed a global improvement in symptoms and functioning. The systematic review also highlighted the fact that the side effects of the drug were 'severe and debilitating', including sedation, considerable weight gain, a lowering of blood pressure, and an increased risk of acute movement disorders. They also noted ...
Propiomazine, also known as 10-(2-dimethylaminopropyl)-2-propionylphenothiazine or as propionylpromethazine, is a phenothiazine derivative [4] and is structurally related to promethazine. The compound is provided medically as the hydrochloride and maleate salts .
Levomepromazine, also known as methotrimeprazine, is a phenothiazine neuroleptic drug.Brand names include Nozinan, Levoprome, Detenler, Hirnamin, Levotomin and Neurocil. It is a low-potency antipsychotic (approximately half as potent as chlorpromazine) with strong analgesic, hypnotic and antiemetic properties that are primarily used in palliative care.
8-Chlorotheophylline, also known as 1,3-dimethyl-8-chloroxanthine, is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine. [1] Its main use is in combination (salt) with diphenhydramine in the antiemetic dimenhydrinate (Dramamine).
Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects. [1] Like all first-generation antihistamines, it is sedating. [2] [3] Patented in 1960, it came into medical use in 1967. [4]
As with many antihistamines, the most common side effect is drowsiness. [1] Today, Triprolidine is used less frequently and has been replaced in popular medications by other antihistamines like Diphenhydramine, Promethazine, Chlorpheniramine, as well as second generation antihistamines like Loratadine and Fexofenadine.
Cyamemazine differs from other phenothiazine neuroleptics in that aside from the usual profile of dopamine, α 1-adrenergic, H 1, and mACh receptor antagonism, [9] it additionally produces potent blockade of several serotonin receptors, including 5-HT 2A, 5-HT 2C, and 5-HT 7.
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