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Lindane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA A receptor-chloride channel complex at the picrotoxin binding site. In humans, lindane affects the nervous system, liver, and kidneys, and may well be a carcinogen. [6] [7] Whether lindane is an endocrine disruptor is unclear. [8] [9] [10]
For a treatment with louse comb alone, it is recommended to comb the hair for an hour to an hour and a half (depending the length and type of the hair) daily or every second day for 14 days. Wetting the hair especially with water and shampoo or conditioner will facilitate the combing and the removal of lice, eggs and nits. [21] [22] [23] [24]
Lindane is still used in a shampoo form in some non-European countries. Its licence was withdrawn by the European Medicines Agency in 2008. [ 2 ] It may be considered as a last resort in some people who show resistance to other treatments, but is not recommended to be used for a second round of treatment.
Permethrin, sulfur, lindane, dicophane, benzyl benzoate, ivermectin and crotamiton are well known ectoparasiticides. [2] Additionally, ectoparasiticides have been used to safely contaminate rhinoceros horns with hopes of it deterring the demand for these horns on the black market.
Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8]It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them.
Recent case studies report high rates of childhood brain cancer due to treatment with Lindane shampoo. Furthermore, studies have proven that Lindane causes a potentially fatal or lifetime condition called aplastic anemia, the deficiency of essential nutrients in the blood and a precursor to leukemia.
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