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  2. Sumatriptan - Wikipedia

    en.wikipedia.org/wiki/Sumatriptan

    The most common side effects [14] reported by at least 2% of patients in controlled trials of sumatriptan (25-, 50-, and 100-mg tablets) for migraine are atypical sensations (paresthesias and warm/cold sensations) reported by 4% in the placebo group and 5–6% in the sumatriptan groups, pain and other pressure sensations (including chest pain ...

  3. Triptan - Wikipedia

    en.wikipedia.org/wiki/Triptan

    [10] [14] For sumatriptan, a number of other application forms are marketed: suppositories, a subcutaneous injection, [10] an iontophoretic transdermal patch, which uses low voltage controlled by a pre-programmed microchip to deliver a single dose of sumatriptan through the skin within 30 minutes; [15] a drug-device combination containing ...

  4. Sumatriptan/naproxen - Wikipedia

    en.wikipedia.org/wiki/Sumatriptan/naproxen

    Sumatriptan/naproxen, sold under the brand name Treximet among others, is a fixed-dose combination medication used to treat migraines. [2] It is taken by mouth. [2] It contains sumatriptan, as the succinate, a serotonin 5-hydroxytryptamine (5-HT) 1b/1d receptor agonist (); and naproxen as the sodium salt, a member of the arylacetic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs).

  5. Escitalopram (Lexapro): Everything You Need to Know Before ...

    www.aol.com/escitalopram-lexapro-everything-know...

    For depression, escitalopram is normally prescribed at a dosage of 10mg to 20mg, taken one time per day. For generalized anxiety disorder and other anxiety disorders, escitalopram is prescribed ...

  6. Discovery and development of triptans - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The U.S. Food and Drug Administration (FDA) approved a new drug April 15, 2008, which is a combination of sumatriptan 85 mg and naproxen 500 mg . [24] Triptans and NSAIDs work on distinct mechanism involved in migraine and therefore may offer improved treatment when administrated together.

  7. Naratriptan - Wikipedia

    en.wikipedia.org/wiki/Naratriptan

    A meta-analysis of 53 clinical trials has shown that all triptans are effective for treating migraine at marketed doses and that naratriptan, although less effective than sumatriptan and rizatriptan was more effective than placebo in reducing migraine symptoms at two hours [3] and efficacy was demonstrated in almost two thirds of subjects after four hours of treatment.

  8. Defined daily dose - Wikipedia

    en.wikipedia.org/wiki/Defined_Daily_Dose

    The WHO's definition is: "The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults." [ 1 ] The Defined Daily Dose was first developed in the late 1970s.

  9. 5-HT3 antagonist - Wikipedia

    en.wikipedia.org/wiki/5-HT3_antagonist

    5-HT 3 receptor antagonist; highest affinity for 5-HT 3 receptor in this class 40 hours CYP1A2, CYP2D6, CYP3A3/4/5 [32] 0.25 mg dose Ramosetron: Benzimidazole derivative 5-HT 3 receptor antagonist 5.8 hours 300 μg/kg Tropisetron [30] Indole: 5-HT 3 receptor antagonist 5.6 hours CYP 3A3/4/5, CYP2D6: 200 μg/kg Vortioxetine: Phenylpiperazine

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