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Vitamin C in grapefruit helps promote collagen production, which supports skin health, registered dietitian Samantha Cassetty notes, including grapefruit on her list of the healthiest fruits.
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
Grapefruit juice may potentially reduce the effectiveness of tamoxifen. [84] Trazodone (Desyrel): Little or no interaction with grapefruit juice. [85] Verapamil (Calan SR, Covera HS, Isoptin SR, Verelan): atrioventricular conduction disorders. [61] Warfarin (coumadin) [86] Zolpidem (Ambien): Little or no interaction with grapefruit juice [85]
The grapefruit is a subtropical citrus tree grown for its fruit which was originally named the "forbidden fruit" of Barbados. [3] The fruit was first documented in 1750 by Rev. Griffith Hughes when describing specimens from Barbados. [4] All parts of the fruit can be used. The fruit is mainly consumed for its tangy juice. [5]
Fruits can provide essential nutrients, fiber and a host of other health benefits. If you enjoy fruits frequently, that's great. ... Lighter Side. Politics. Science & Tech. Sports. Weather. 24/7 Help.
Naringenin is a flavanone from the flavonoid group of polyphenols. [2] It is commonly found in citrus fruits, especially as the predominant flavonone in grapefruit. [2]The fate and biological functions of naringenin in vivo are unknown, remaining under preliminary research, as of 2024. [2]
Grapefruit–drug interactions are common, as the juice contains furanocoumarins that interfere with the metabolism of many drugs. This can prolong and intensify the effects of those drugs, leading to multiple side-effects such as abnormal heart rhythms, bleeding inside the stomach, low blood pressure, difficulty breathing, and dizziness.
The effects of grapefruit last from 3–7 days, with the greatest effects when juice is taken an hour previous to administration of the drug. [25] In addition to grapefruit, other fruits have similar effects. Noni (Morinda citrifolia), for example, is a dietary supplement typically consumed as a juice and also inhibits CYP3A4. [26]