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  2. Electronic patient-reported outcome - Wikipedia

    en.wikipedia.org/wiki/Electronic_patient...

    As well as clinical trial use, ePRO methods may be used to support patients in regular care. An example of this is the collection of symptom data from patients undergoing chemotherapy, using handheld diaries. This allows clinic staff to monitor outpatients, and to identify the occurrence of adverse reactions that may require intervention. [18]

  3. Open-label trial - Wikipedia

    en.wikipedia.org/wiki/Open-label_trial

    This contrasts with a double-blinded trial, where information is withheld both from the researchers and the participants to reduce bias. [ 2 ] [ 3 ] Open-label trials may be appropriate for comparing two similar treatments to determine which is most effective, such as a comparison of different prescription anticoagulants , [ 4 ] or possible ...

  4. Lost to follow-up - Wikipedia

    en.wikipedia.org/wiki/Lost_to_follow-up

    These patients can become lost for many reasons. Without properly informing the investigator associated with the clinical trial, they may have opted to withdraw from the clinical trial, moved away from the particular study site during the clinical trial, become ill and unable to communicate, are missing or are deceased. [1]

  5. Glossary of clinical research - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_clinical_research

    A clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known treatments. Clinical trials (also called medical research and research studies) are used to determine whether new drugs or treatments are both safe and effective.

  6. Clinical trial - Wikipedia

    en.wikipedia.org/wiki/Clinical_trial

    A clinical trial participant receives an injection. Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further ...

  7. Clinical research - Wikipedia

    en.wikipedia.org/wiki/Clinical_research

    Clinical research is a branch of medical research that involves people and aims to determine the effectiveness and safety of medications, devices, diagnostic products, and treatment regimens intended for improving human health.

  8. Blinded experiment - Wikipedia

    en.wikipedia.org/wiki/Blinded_experiment

    In a blind or blinded experiment, information which may influence the participants of the experiment is withheld until after the experiment is complete. Good blinding can reduce or eliminate experimental biases that arise from a participants' expectations, observer's effect on the participants , observer bias , confirmation bias , and other ...

  9. Real world data - Wikipedia

    en.wikipedia.org/wiki/Real_world_data

    The use of real-world data from electronic health records and digital health-monitoring devices is also given as an example of general Post-Market Clinical Followup (PMCF) information for medical devices in the guideline "MDCG 2022-21 Guidance on Periodic Safety Update Report (PSUR) according to Regulation (EU) 2017/745 (MDR)" from December ...