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Adapted from Ellis, Frank (2002) Paracetamol: a curriculum resource, Cambridge: Royal Society of Chemistry ISBN: 0-85404-375-6. Author: WhiteTimberwolf, PNG version: Rifleman 82: Permission (Reusing this file)
Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Paracetamol relieves pain in both acute mild migraine and episodic tension headache.
An industrial synthesis of paracetamol developed by Hoechst–Celanese involves the conversion of a methyl ketone to an acetanilide via a Beckmann rearrangement. [ 15 ] The thermal rearrangement that occurs in the synthesis of ketamine was claimed to be a Beckmann rearrangement according to: url .
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A process flow diagram (PFD) is a diagram commonly used in chemical and process engineering to indicate the general flow of plant processes and equipment. The PFD displays the relationship between major equipment of a plant facility and does not show minor details such as piping details and designations.
English: The direct, one-pot synthesis of paracetamol from hydroquinone and ammonium acetate as described in Green Chem., 2014,16, 2997-3002 Date 31 January 2021
The photo-Fries rearrangement can likewise give [1,3] and [1,5] products, [7] [8] which involves a radical reaction mechanism. This reaction is also possible with deactivating substituents on the aromatic group. Because the yields are low this procedure is not used in commercial production.
Organic synthesis is a special type of chemical synthesis dealing with the synthesis of organic compounds. For the total synthesis of a complex product, multiple procedures in sequence may be required to synthesize the product of interest, needing a lot of time. A purely synthetic chemical synthesis begins with basic lab compounds.