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Clindamycin may prolong the effects of neuromuscular-blocking drugs, such as succinylcholine and vecuronium. [55] [56] [57] Its similarity to the mechanism of action of macrolides and chloramphenicol means they should not be given simultaneously, as this causes antagonism [26] and possible cross-resistance. [medical citation needed]
Macrolides belong to the polyketide class of natural products. Some macrolides have antibiotic or antifungal activity and are used as pharmaceutical drugs. Rapamycin is also a macrolide and was originally developed as an antifungal, but has since been used as an immunosuppressant drug and is being investigated as a potential longevity ...
Of the lincosamides, clindamycin is most commonly used within the clinic due to its higher bioavailability, higher oral absorption and efficacy within the target organism spectrum. [23] Lincosamides are generally the first-choice use antibiotic class in veterinary microbiology, most commonly used to combat skin infections. [7]
Severe side effects include an increased risk of tendon rupture, hallucinations, and nerve damage. [5] In people with myasthenia gravis, there is worsening muscle weakness. [5] Rates of side effects appear to be higher than some groups of antibiotics such as cephalosporins but lower than others such as clindamycin. [7]
Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides. Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin , teicoplanin , telavancin , ramoplanin and decaplanin, corbomycin , complestatin and the antitumor antibiotic ...
Lincomycin is a lincosamide antibiotic that comes from the actinomycete Streptomyces lincolnensis. [3] A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality. [4] It was released for medical use in September 1964. [5]
Bottom line: Most drugs carry a risk, but if you've been prescribed an oral or injected fluoroquinolone and you're concerned about side effects, be sure to talk to your doctor about switching.
Common side effects include gastrointestinal effects such as nausea, vomiting, and diarrhea, as well as headache and insomnia. Postmarketing surveillance has revealed a variety of relatively rare but serious adverse effects associated with all members of the fluoroquinolone antibacterial class.
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related to: macrolide antibiotics clindamycin side effects mayo clinic- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
"GoodRx app has saved consumers $10 billion." - Fox Business