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  2. Graves' ophthalmopathy - Wikipedia

    en.wikipedia.org/wiki/Graves'_ophthalmopathy

    In mild disease, patients present with eyelid retraction. In fact, upper eyelid retraction is the most common ocular sign of Graves' orbitopathy. This finding is associated with lid lag on infraduction (Von Graefe's sign), eye globe lag on supraduction (Kocher's sign), a widened palpebral fissure during fixation (Dalrymple's sign) and an incapacity of closing the eyelids completely ...

  3. Photophobia - Wikipedia

    en.wikipedia.org/wiki/Photophobia

    Photophobia is a medical symptom of abnormal intolerance to visual perception of light. [1] As a medical symptom, photophobia is not a morbid fear or phobia, but an experience of discomfort or pain to the eyes due to light exposure or by presence of actual physical sensitivity of the eyes, [2] though the term is sometimes additionally applied to abnormal or irrational fear of light, such as ...

  4. Signs and symptoms of Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    A possible explanation for the mental symptoms of sub-clinical thyroid disease, might be found in the fact that the brain has among the highest expression of THR's [clarification needed], and that neurons are often more sensitive than other tissues to thyroid abnormalities, including sub-clinical hyperthyroidism and thyrotoxicosis.

  5. Viridian's drug cuts thyroid eye disease symptoms in late ...

    www.aol.com/news/viridian-says-thyroid-eye...

    TED causes inflammation and damage to the tissues around the eye and usually occurs in people with Graves' disease, an immune system disorder that results in overproduction of thyroid hormones.

  6. Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Graves'_disease

    Thyroid-associated ophthalmopathy (TAO), or thyroid eye disease (TED), is the most common extrathyroidal manifestation of Graves' disease. It is a form of idiopathic lymphocytic orbital inflammation , and although its pathogenesis is not completely understood, autoimmune activation of orbital fibroblasts , which in TAO express the TSH receptor ...

  7. Infiltrative ophthalmopathy - Wikipedia

    en.wikipedia.org/wiki/Infiltrative_ophthalmopathy

    Infiltrative ophthalmopathy is found in 5-10% of patients with Graves disease and resembles exophthalmos, except that the blurry or double vision is acquired because of weakness in the ocular muscles of the eye. [1] [2] In addition, there is no known correlation with the patient's thyroid levels.

  8. Photosensitivity in humans - Wikipedia

    en.wikipedia.org/wiki/Photosensitivity_in_humans

    Light sensitivity or photosensitivity refers to a notable or increased reactivity to light. Apart from vision, human beings have many physiological and psychological responses to light. In rare individuals an atypical response may result in serious discomfort, disease, or injury. Some drugs have a photosensitizing effect.

  9. Dalrymple's sign - Wikipedia

    en.wikipedia.org/wiki/Dalrymple's_sign

    Dalrymple's sign is a widened palpebral (eyelid) opening, or eyelid spasm, seen in thyrotoxicosis (as seen in Graves' disease, exophthalmic goitre and other hyperthyroid conditions), causing abnormal wideness of the palpebral fissure.

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