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Pamrevlumab (INN; [1] development code FG-3019) is a humanized monoclonal antibody designed for the treatment of idiopathic pulmonary fibrosis and pancreatic cancer. It binds to the connective tissue growth factor (CTGF) protein. [2] This drug was developed by FibroGen, Inc. [3]
Pamrevlumab [12] mab: human: connective tissue growth factor (CTGF) idiopathic pulmonary fibrosis (IPF), pancreatic cancer Panitumumab [69] Vectibix: mab: human: epidermal growth factor receptor (EGFR) Y: colorectal cancer: Pankomab: mab: humanized: tumor specific glycosylation of MUC1: ovarian cancer Panobacumab [98] mab: human: Pseudomonas ...
Combined pulmonary fibrosis and emphysema (CPFE) is a rare syndrome that shows upper-lobe emphysema, together with lower-lobe interstitial fibrosis. This is diagnosed by CT scan . [ 34 ] This syndrome presents a marked susceptibility for the development of pulmonary hypertension .
Arrange a rack in center of oven; preheat to 325°. Pat beef dry with paper towels. Using a spice grinder, mortar and pestle, or zip-top bag and a rolling pin, pulse or crush onion soup mix ...
The association of idiopathic retroperitoneal fibrosis with various immune-related conditions and response to immunosuppression led to a search for an autoimmune cause of idiopathic RPF. [5] [6] Many of these previously idiopathic cases can now be attributed to IgG4-related disease, an autoimmune disorder proposed in 2003.
The NFC wild-card game between the Los Angeles Rams and Minnesota Vikings is being moved to Arizona, the NFL announced Thursday. The game remains scheduled for Monday at 5 p.m. PT, but will now be ...
The first College Football Playoff semifinal will feature Penn State and Notre Dame. A breakdown of the keys to victory in the Orange Bowl.
It is intended for the treatment of idiopathic pulmonary fibrosis (IPF), focal segmental glomerulosclerosis, and cancer [2] [3] (kidney cancer and melanoma). It binds to and inhibits all isoforms of the protein transforming growth factor beta (TGF-β).