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  2. Klinefelter syndrome - Wikipedia

    en.wikipedia.org/wiki/Klinefelter_syndrome

    This XXY chromosome arrangement is one of the most common genetic variations from the XY karyotype, occurring in approximately one in 500 live male births. [4] [13] [36] In mammals with more than one X chromosome, the genes on all but one X chromosome are not expressed; this is known as X inactivation. This happens in XXY males, as well as ...

  3. X chromosome - Wikipedia

    en.wikipedia.org/wiki/X_chromosome

    The X chromosome is one of the two sex chromosomes in many organisms, including mammals, and is found in both males and females. It is a part of the XY sex ...

  4. XX male syndrome - Wikipedia

    en.wikipedia.org/wiki/XX_male_syndrome

    [22] [21] The X chromosome with the SRY gene is preferentially chosen to be the active X chromosome 90% of the time, which explains complete male phenotype being observed often in SRY-positive XX males. [22] [21] In the remaining 10%, however, X inactivation occurs on the X chromosome with the SRY gene, thereby silencing it and resulting in ...

  5. XXXY syndrome - Wikipedia

    en.wikipedia.org/wiki/XXXY_syndrome

    XXXY syndrome is a genetic condition characterized by a sex chromosome aneuploidy, where individuals have two extra X chromosomes. [3] People in most cases have two sex chromosomes: an X and a Y or two X chromosomes. The presence of one Y chromosome with a functioning SRY gene causes the expression of genes that determine maleness. Because of ...

  6. XXYY syndrome - Wikipedia

    en.wikipedia.org/wiki/XXYY_syndrome

    48,XXYY syndrome is a condition related to the X and Y chromosomes (the sex chromosomes). People normally have 46 chromosomes in each cell.Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics.

  7. Sexual differentiation in humans - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation_in...

    In the absence of a Y chromosome, the fetus will undergo female development. This is because of the presence of the sex-determining region of the Y chromosome, also known as the SRY gene. [5] Thus, male mammals typically have an X and a Y chromosome (XY), while female mammals typically have two X chromosomes (XX).

  8. Pseudoautosomal region - Wikipedia

    en.wikipedia.org/wiki/Pseudoautosomal_region

    PAR1 comprises 2.6 Mbp of the short-arm tips of both X and Y chromosomes in humans and great apes (X and Y are 154 Mbp and 62 Mbp in total). PAR2 is at the tips of the long arms, spanning 320 kbp. [5] The monotremes, including the platypus and echidna, have a multiple sex chromosome system, and consequently have 8 pseudoautosomal regions. [6]

  9. XO sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XO_sex-determination_system

    Most spiders have a variation of the XO system in which males have two different X chromosomes (X 1 X 2 O), while females have a pair of X 1 chromosomes and a pair of X 2 chromosomes (X 1 X 1 X 2 X 2). [1] Some spiders have more complex systems involving as many as 13 different X chromosomes. [1] Some Drosophila species have XO males. [10]