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  2. Ototoxicity - Wikipedia

    en.wikipedia.org/wiki/Ototoxicity

    Ototoxicity-induced hearing loss typically impacts the high frequency range, affecting above 8000 Hz prior to impacting frequencies below. [8] There is not global consensus on measuring severity of ototoxicity-induced hearing loss as there are many criteria available to define and measure ototoxicity-induced hearing loss.

  3. Chemotherapy-induced peripheral neuropathy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy-induced...

    [6] [7] Specific side effects of platinum compounds include hearing loss, tinnitus, and dysesthesia. These symptoms generally begin with the or third cycle of treatment and can last long after treatment completion. Indeed, the “coasting” phenomenon mentioned in the Symptoms section is a direct effect of platinum agents. Of the platinum ...

  4. Ototoxic medication - Wikipedia

    en.wikipedia.org/wiki/Ototoxic_medication

    This protective agent was also found to be associated with the survival of cochlear spiral ganglion neurones after hearing loss or deafness. [35] Audiological management can be implemented, for example, by providing hearing aids. In more seriously affected patients, cochlear implantation may be considered and discussed with the patient.

  5. After Two FDA Rejections, Fennec Pharma Lead Drug ... - AOL

    www.aol.com/two-fda-rejections-fennec-pharma...

    The FDA approved Fennec Pharmaceuticals Inc's (NASDAQ: FENC) Pedmark to reduce the risk of chemo-induced ototoxicity in pediatric patients. Pedmark is indicated for pediatric patients one month of ...

  6. What Is Sensorineural Hearing Loss (SNHL) | Causes ... - AOL

    www.aol.com/lifestyle/sensorineural-hearing-loss...

    In this article, we’re taking a closer look at sensorineural hearing loss (SNHL) is, its causes, and potential treatments.

  7. Sodium thiosulfate (medical use) - Wikipedia

    en.wikipedia.org/wiki/Sodium_thiosulfate...

    In September 2022, the U.S. Food and Drug Administration (FDA) approved sodium thiosulfate under the brand name Pedmark to lessen the risk of ototoxicity and hearing loss in infant, child, and adolescent cancer patients receiving the chemotherapy medication cisplatin. [3] [13] [14]

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