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2. Vitamin B12 Is a Power Nutrient. Here's How to Know If ... - AOL

   www.aol.com/vitamin-b12-power-nutrient-heres...

   “Vitamin B12 requirements are low because we can store up to 2,500 micrograms in the liver,” says Ryan D. Andrews, R.D., C.S.C.S., principal nutritionist at Precision Nutrition. So target just ...

3. The Top Signs You Have a Vitamin B12 Deficiency - AOL

   www.aol.com/top-sign-vitamin-b12-deficiency...

   When is the best time to take B12? ... your ability to absorb vitamin B12 may decline so I often recommend up to 1,000 mcg per day.” ... The most surefire way to get sufficient B12 from food is ...

4. How vitamin B12 could give you an energy boost - AOL

   www.aol.com/finance/vitamin-b12-could-energy...

   That includes folks with an autoimmune disorder called pernicious anemia, who are unable to absorb B12, and people who take a lot of over-the-counter stomach-acid reducers, like famotidine ...

5. Vitamin B12 - Wikipedia

   en.wikipedia.org/wiki/Vitamin_B12

   Vitamin B 12 is absorbed by a B 12-specific transport proteins or via passive diffusion. [12] Transport-mediated absorption and tissue delivery is a complex process involving three transport proteins: haptocorrin (HC), intrinsic factor (IF) and transcobalamin II (TC2), and respective membrane receptor proteins. HC is present in saliva.

6. Intrinsic factor - Wikipedia

   en.wikipedia.org/wiki/Intrinsic_factor

   Because vitamin B 12 absorption is a multistep process that involves the stomach, pancreas and small intestine, and is mediated by two carriers: Haptocorrin and intrinsic factor, and because Haptocorrin (transcobalamin I) binds to vitamin B 12, and Vitamin B 12 is acid-sensitive, when vitamin B 12 binds to Haptocorrin it can safely pass through ...

7. Transcobalamin - Wikipedia

   en.wikipedia.org/wiki/Transcobalamin

   It primarily serves to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a HC-Vitamin B 12 complex. Once the complex has traveled to the more pH-neutral duodenum, pancreatic proteases degrade haptocorrin, releasing free cobalamin, which now binds to intrinsic factor for absorption by ileal enterocytes.