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Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is taken orally or intravenously for rheumatoid arthritis , psoriasis , Crohn's disease , nephrotic syndrome , eczema , and in organ transplants to prevent rejection .
Dry eye syndrome can lead to blurred vision, instability of the tear film, increased risk of damage to the ocular surface such as scarring of the cornea, and changes in the eye including the neurosensory system. [2] [6] Dry eye occurs when either the eye does not produce enough tears or when the tears evaporate too quickly. [2]
Dorzolamide, sold under the brand name Trusopt among others, is a medication used to treat high pressure inside the eye, including in cases of glaucoma. [3] It is used as an eye drop. [3] Effects begin within three hours and last for at least eight hours. [3] It is also available as the combination dorzolamide/timolol. [3] [4]
Cyclophosphamide (CP), also known as cytophosphane among other names, [3] is a medication used as chemotherapy and to suppress the immune system. [4] As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. [4]
It is commonly used as an eye drop during pediatric eye examinations to dilate the eye and prevent the eye from focusing/accommodating (cycloplegic). Cyclopentolate [ citation needed ] or atropine can also be administered to reverse muscarinic and central nervous system effects of indirect cholinomimetic (anti-AChase) administration.
Visual or vision impairment (VI or VIP) is the partial or total inability of visual perception.In the absence of treatment such as corrective eyewear, assistive devices, and medical treatment, visual impairment may cause the individual difficulties with normal daily tasks, including reading and walking. [6]
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