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The synergy between trimethoprim and sulfamethoxazole was first described in the late 1960s. [25] [26] [27] Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. They are given in a one-to-five ratio in their tablet ...
A combination antibiotic is one in which two ingredients are added together for additional therapeutic effect. [1] One or both ingredients may be antibiotics. [1]Antibiotic combinations are increasingly important because of antimicrobial resistance. [2]
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. [1] [2] It is taken orally (swallowed by mouth). [1]
This page was last edited on 20 October 2024, at 19:30 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
The antacids have no interaction between them, so they would be considered to have additive effect when taken together. Drugs that are in the same class, but do not have the same target, may also act additively by interacting with different targets in the same pathway. For example, propofol and sevoflurane can both produce anesthetic effects. [6]
Trimethoprim-Sulfamethoxazole (Co-trimoxazole) Bactrim, Septra ... But Tetracycline cannot be taken together with all dairy products, aluminium, iron and zinc ...
Whether it's a holiday potluck or summer barbecue with friends, eating past the point of fullness happens—and that’s totally normal. Sure, it’s not something we’d recommend doing every day ...
Certain sulfonamides (sulfadiazine or sulfamethoxazole) are sometimes mixed with the drug trimethoprim, which acts against dihydrofolate reductase. As of 2013, the Republic of Ireland is the largest exporter worldwide of sulfonamides, accounting for approximately 32% of total exports. [16]
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