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Chronological table of epidemic and pandemic events in human history Event Years Location Disease Death toll (estimate) Ref. 1350 BC plague of Megiddo c. 1350 BC Megiddo, land of Canaan: Amarna letters EA 244, Biridiya, mayor of Megiddo complains to Amenhotep III of his area being "consumed by death, plague and dust" Unknown [29]
The Black Death was a bubonic plague pandemic that occurred in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [2] perished, perhaps 50% of Europe's 14th century population. [3]
Distribution of plague infected animals and people, as of 1998. Plague cases were massively reduced during the second half of the 20th century, but outbreaks still occurred, especially in developing countries. Between 1954 and 1997, human plague was reported in 38 countries, making the disease a re-emerging threat to human health. [65]
One of the worst plagues in history, the Black Death arrived on the shores of Europe in 1347. Five years later, around 25 to 50 million people were dead across the continent.
Plague, one of the deadliest bacterial infections in human history, caused an estimated 50 million deaths in Europe during the Middle Ages when it was known as the Black Death.
The full effect of the plague was felt in the capital early the next year. [32] Conditions in London were ideal for the plague: the streets were narrow and flowing with sewage, and houses were overcrowded and poorly ventilated. [33] By March 1349 the disease was spreading haphazardly across all of southern England. [34]
The Spanish Flu, the second deadliest pandemic in history after the bubonic plague, along with the aftermath of World War I and ensuing political and social chaos, made 1918 a tough time to be alive.
The plague often killed 10% of a community in less than a year—in the worst epidemics, such as at Norwich in 1579 and Newcastle in 1636, as many as 30 or 40%. The most general outbreaks in Tudor and Stuart England, all coinciding with years of plague in Germany and the Low Countries , seem to have begun in 1498, 1535, 1543, 1563, 1589, 1603 ...