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Varicella zoster virus (VZV), also known as human herpesvirus 3 (HHV-3, HHV3) or Human alphaherpesvirus 3 (taxonomically), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children.
Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 Amantadine: Influenza: Influenza A virus M2 proton channel antagonist Ampligen: Avian Influenza: Immunomodulatory double-stranded RNA: Amprenavir (Agenerase) HIV Protease ...
Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. [6] Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein–Barr virus infection.
The varicella vaccine is recommended in many countries. [12] Some countries require the varicella vaccination or an exemption before entering elementary school. A second dose is recommended five years after the initial immunization. [45] A vaccinated person is likely to have a milder case of chickenpox if they become infected. [46]
Vaccine doses already held by practitioners could still be administered up to the expiration date (none expired later than November 2020). [51] [12] The US Centers for Disease Control and Prevention (CDC) recommends that healthy adults 50 years and older get two doses of Shingrix, at least two months apart. Initial clinical trials only tested a ...
The second dose, if given, should occur at least one to three months later. [10] The second dose, if given, provides the additional benefit of improved protection against all varicella. [44] This vaccine is a shot given subcutaneously (under the skin). It is recommended for all children under 13 and for everyone 13 or older who has never had ...
Nine herpesvirus types are known to primarily infect humans, [7] at least five of which are extremely widespread among most human populations, and which cause common diseases: herpes simplex 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial and genital herpes), varicella zoster (or HHV-3; the cause of ...
The general idea behind modern antiviral drug design is to identify viral proteins, or parts of proteins, that can be disabled. [11] [13] These "targets" should generally be as unlike any proteins or parts of proteins in humans as possible, to reduce the likelihood of side effects and toxicity. [8]