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The 1993 study by Hamer et al. examined 114 families of gay men in the United States and found increased rates of homosexuality among maternal uncles and cousins, but not among paternal relatives. This pattern of inheritance suggested that there might be linked genes on the X chromosome , since males always inherit their copy of the X ...
This was popularly dubbed the "gay gene" in the media, causing significant controversy. In 1998, Sanders et al. [citation needed] reported on their similar study, in which they found that 13% of uncles of gay brothers on the maternal side were homosexual, compared with 6% on the paternal side. [33]
The idea of epigenetics and gene expression has been a theory applied to the origins of homosexuality in humans. One team of researchers examined the effects of epi-marks buffering XX fetuses and XY fetuses from certain androgen exposure and used published data on fetal androgen signaling and gene regulation through non-genetic changes in DNA ...
The fraternal birth order effect has been described by one of its proponents as "the most consistent biodemographic correlate of sexual orientation in men". [5] In 1958, it was reported that homosexual men tend to have a greater number of older siblings (i.e., a 'later/higher birth order') than comparable heterosexual men and in 1962, these findings were published in detail. [6]
Despite numerous attempts, no "gay gene" has been identified. However, there is substantial evidence for a genetic basis of homosexuality, especially in males, based on twin studies; some association with regions of Chromosome 8, the Xq28 locus on the X chromosome, and other sites across many chromosomes. [170
The Science of Desire: The Search for the Gay Gene and the Biology of Behavior is a 1994 book by the geneticist Dean Hamer and the journalist Peter Copeland, in which the authors discuss Hamer's research into the genetics of homosexuality. The book received both positive and mixed reviews.
Dean Hamer (/ ˈ h eɪ m ər /; born May 29, 1951) is an American geneticist, author, and filmmaker.He is known for his research on the role of genetics in sexual orientation and for a series of popular books and films that have changed scientific and public understandings and perceptions of human sexuality and gender.
Burr's "Gay Gene" website, based on his book, was listed as a "hot web site" by The Advocate in 1998. [17] Tom Moon discussed Burr's views in the San Francisco Bay Times. [18] Mass considered Burr a "gay-positive essentialist" and A Separate Creation "a valuable historical document" comparable to the journalist Randy Shilts' And the Band Played ...